HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

The method score is based on:

Property	Details
Experiments	12592385, 26831064, 9662397
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003713 - transcription coactivator activity GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 9 others more... GO:0005737 - cytoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0016604 - nuclear body GO:0032991 - protein-containing complex GO:0045739 - positive regulation of DNA repair GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0070063 - RNA polymerase binding GO:0071356 - cellular response to tumor necrosis factor GO:1990904 - ribonucleoprotein complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	1863
Hs

1	1270

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024