HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 25184681, 25634209, 23074186, 34079125
Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0019899 - enzyme binding
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 183
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024