Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.657

The method score is based on:

Property Details
Experiments 26121674, 27764250, 14654789
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0045892 - negative regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 785
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024