Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: ABRX1 (Q6UWZ7)
BRCA1-A complex subunit Abraxas 1 (Coiled-coil domain-containing protein 98) (Protein FAM175A)
Gene: ABRAXAS1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.764 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19261749, 19261746, 21282113, 19261748, 17525340, 17643121, 17643122, 22357538, 25184681, 26778126, 28398198, 29656893, 30257991, 34591612, 19305427, 23416467 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, unspecified method, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, surface plasmon resonance |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006282 - regulation of DNA repair GO:0006302 - double-strand break repair GO:0007095 - mitotic G2 DNA damage checkpoint signaling and 5 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
