Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: PALB2 (Q86YC2)
Partner and localizer of BRCA2
Gene: PALB2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.766 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25184681, 26649820, 25652403, 28398198, 29656893, 30337689, 34408138, 19268590, 19369211, 24085845, 22193777, 25016020, 22331464, 28319063, 28089683, 19584259, 19553677, 23038782, 23585894 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000724 - double-strand break repair via homologous recombination GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex and 1 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
