HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 1116
+	Hs
		724691 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		148473 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		725099 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Hs
		749791 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		KI20B_HUMAN (386-907): 1.4e-10: 68.2: 21.17
+	Hs
		551628 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		DESP_HUMAN (457-1104): 2.2e-09: 64.3: 13.22
+	Hs
		528393 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH6_HUMAN (3-544): 6.64e-24: 111: 9.47
+	Hs
		522639 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH7_HUMAN (6-513): 7.72e-21: 101: 9.84
+	Hs
		149258 TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		725005 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		725238 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Ce
		136785 UNC89_CAEEL (434-1630): 9.57e-17: 89.4: 11.68		O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15
+	Mm
		1093546 TRI72_MOUSE (18-91): 9.41e-12: 71.5: 30.26		MYH9_MOUSE (1-318): 1.36e-10: 68.2: 8.49