HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: F184A (Q8NB25)
Protein FAM184A
Gene: FAM184A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	25184681
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 1140
+	Hs
		749622 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH14_HUMAN (22-957): 2.61e-26: 119: 12.64
+	Hs
		551628 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		DESP_HUMAN (62-769): 1.49e-25: 117: 15.83
+	Hs
		724691 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH9_HUMAN (636-1135): 4.32e-20: 99.4: 11.00
+	Hs
		725099 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH10_HUMAN (761-1140): 1.43e-16: 87.9: 12.90
+	Hs
		536934 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		F184A_HUMAN (1-1140): 7.61e-89: 313: 100.00
+	Hs
		528393 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH6_HUMAN (1-399): 3.85e-14: 79.8: 10.78
+	Hs
		522639 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH7_HUMAN (1-389): 8.81e-14: 78.6: 11.57
+	Hs
		1189797 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH14_HUMAN (22-957): 2.61e-26: 119: 12.64
+	Hs
		725005 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH9_HUMAN (636-1135): 4.32e-20: 99.4: 11.00
+	Hs
		725238 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH10_HUMAN (761-1140): 1.43e-16: 87.9: 12.90
+	Mm
		1093546 TRI72_MOUSE (18-91): 9.41e-12: 71.5: 30.26		MYH9_MOUSE (624-1128): 1.27e-17: 91.4: 12.03