HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: PPHLN (Q8NEY8)
Periphilin-1 (CDC7 expression repressor) (CR) (Gastric cancer antigen Ga50)
Gene: PPHLN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	24981860, 22990118
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005694 - chromosome GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 458
+	Hs
		1243726 TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12		PPHLN_HUMAN (1-458): 0: 722: 100.00