HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: CIP2A (Q8TCG1)
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)
Gene: CIP2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29656893, 34591612
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005694 - chromosome GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006974 - DNA damage response
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 905
+	Hs
		749488 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		DCTN1_HUMAN (546-889): 2.81e-19: 95.9: 9.97
+	Hs
		1253520 TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12		CIP2A_HUMAN (1-905): 0: 982: 100.00
+	Hs
		584960 RO52_HUMAN (15-390): 2.55e-68: 241: 12.86		DCTN1_HUMAN (546-889): 2.81e-19: 95.9: 9.97
+	Hs
		522639 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH7_HUMAN (471-889): 5.54e-15: 82: 13.59
+	Hs
		528393 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH6_HUMAN (554-885): 1.12e-14: 80.9: 12.00
+	Hs
		255282 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		HIP1R_HUMAN (691-884): 5.73e-09: 62: 15.20
+	Hs
		1019301 TRI26_HUMAN (12-287): 2.53e-51: 193: 14.53		DCTN1_HUMAN (546-889): 2.81e-19: 95.9: 9.97