HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: ATRIP (Q8WXE1)
ATR-interacting protein (ATM and Rad3-related-interacting protein)
Gene: ATRIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	29656893, 17616665, 24073851
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 791
+	Hs
		1263396 TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12		ATRIP_HUMAN (1-791): 0: 1200: 100.00
+	Xl
		1130840 TOB1A_XENLA (1139-1859): 6.1e-144: 487: 12.76		Q5SDB4_XENLA (28-790): 0: 1051: 43.22