HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: TFG (Q92734)
Protein TFG (TRK-fused gene protein)
Gene: TFG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26831064, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 400
+	Hs
		302262 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		SC31A_HUMAN (98-394): 1.59e-27: 116: 13.29
+	Hs
		749914 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		OGFR_HUMAN (124-395): 2.69e-23: 103: 14.79
+	Hs
		749430 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		BPTF_HUMAN (93-397): 1.7e-20: 96.1: 14.15
+	Hs
		123868 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		SPT5H_HUMAN (105-292): 2.84e-09: 61.1: 9.62
+	Hs
		749275 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		SC24C_HUMAN (97-340): 3.76e-09: 60.7: 14.69
+	Hs
		1149892 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		TFG_HUMAN (1-400): 4.64e-79: 250: 100.00
+	Hs
		1270124 BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98		TFG_HUMAN (1-400): 4.64e-79: 250: 100.00
+	Hs
		537041 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		SHAN3_HUMAN (126-398): 1.2e-16: 84.2: 18.18
+	Hs
		537122 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		MAGL2_HUMAN (96-386): 1.03e-15: 81.1: 13.70
+	Hs
		124063 BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98		SPT5H_HUMAN (105-292): 2.84e-09: 61.1: 9.62