HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: RPGR1 (Q96KN7)
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1)
Gene: RPGRIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.504

Property	Details
Experiments	22990118
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 1286
+	Hs
		148473 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		CTRO_HUMAN (10-684): 2.86e-34: 146: 11.90
+	Hs
		724691 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH9_HUMAN (12-620): 4.46e-21: 102: 9.69
+	Hs
		551628 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		DESP_HUMAN (57-812): 4.84e-18: 92.9: 8.83
+	Hs
		725099 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		MYH10_HUMAN (7-528): 2.02e-14: 81: 10.48
+	Hs
		536879 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		FTM_HUMAN (1-1284): 0: 717: 29.80
+	Mm
		1143601 TRI27_MOUSE (13-390): 9.45e-70: 246: 11.74		FTM_MOUSE (1-1284): 0: 694: 29.93
+	Hs
		149258 TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52		CTRO_HUMAN (10-684): 2.86e-34: 146: 11.90
+	Hs
		528393 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH6_HUMAN (2-676): 5.09e-26: 119: 8.06
+	Hs
		522639 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH7_HUMAN (1-499): 3.1e-16: 86.7: 9.88
+	Hs
		725005 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH9_HUMAN (12-620): 4.46e-21: 102: 9.69
+	Hs
		725238 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		MYH10_HUMAN (7-528): 2.02e-14: 81: 10.48
+	Mm
		1093546 TRI72_MOUSE (18-91): 9.41e-12: 71.5: 30.26		MYH9_MOUSE (13-664): 2.89e-20: 99: 10.63