Interactor 1: CUE1 (P38428)
Coupling of ubiquitin conjugation to ER degradation protein 1 (Kinetochore-defect suppressor 4)
Gene: CUE1
Interactor 2: UBC7 (Q02159)
Ubiquitin-conjugating enzyme E2 7 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 7) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC7
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.90 | 0.928 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9388185, 17310239, 19366730, 37066402, 18321851, 25646477, 32588820, 37968396, 23665230 |
| Identification Methods | pull down, biochemical, affinity chromatography technology, x-ray crystallography, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cue1_U7BR~UQ_con |
| Common GO terms | GO:0000837 - Doa10p ubiquitin ligase complex GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0036503 - ERAD pathway and 1 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
