HitPredict

Interactor 1: PSB1 (P38624)
Proteasome subunit beta type-1 (EC 3.4.25.1) (Macropain subunit PRE3) (Multicatalytic endopeptidase complex subunit PRE3) (Proteasome component PRE3) (Proteinase YSCE subunit PRE3)
Gene: PRE3

Interactor 2: ECM29 (P38737)
Proteasome component ECM29 (Extracellular mutant protein 29)
Gene: ECM29

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 37968396, 21321079
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 215 Sc			1 1868
+	Sc
		625930 PSB2_YEAST (2-214): 1.18e-69: 214: 26.73		ECM29_YEAST (1-1868): 0: 1493: 100.00
+	Sc
		675414 PSB5_YEAST (13-209): 4.66e-69: 214: 27.14		ECM29_YEAST (1-1868): 0: 1493: 100.00
+	Sc
		619356 PSA3_YEAST (5-215): 4.55e-69: 213: 17.20		ECM29_YEAST (1-1868): 0: 1493: 100.00
+	Hs
		656251 PSA5_HUMAN (5-215): 1e-74: 227: 15.32		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		656125 PSB9_HUMAN (9-211): 2.36e-74: 225: 45.10		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		638148 PSA4_HUMAN (5-215): 9.98e-73: 223: 15.46		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		656731 PSB5_HUMAN (14-205): 3.86e-70: 216: 27.32		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		893689 PSA6_HUMAN (5-214): 5.29e-70: 215: 16.90		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		1139426 PSB7_HUMAN (17-209): 1.35e-68: 213: 30.93		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		156310 PSA7_HUMAN (6-214): 3.71e-69: 213: 16.13		ECM29_HUMAN (9-1753): 0: 1033: 22.20
+	Hs
		656268 PSA5_HUMAN (5-215): 1e-74: 227: 15.32		CAND1_HUMAN (1380-1695): 2.42e-09: 64.7: 13.23