Interactor 1: NSE2 (P38632)
E3 SUMO-protein ligase MMS21 (EC 2.3.2.-) (E3 SUMO-protein transferase MMS21) (Methyl methanesulfonate-sensitivity protein 21) (Non-structural maintenance of chromosome element 2) (Non-SMC element 2)
Gene: MMS21

Interactor 2: SMC5 (Q08204)
Structural maintenance of chromosomes protein 5
Gene: SMC5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 25764370, 15738391, 19748359, 19141609, 33941673, 16554755, 29769404, 31801080, 37968396, 21999667, 19652357, 14690591
Identification Methods anti tag coimmunoprecipitation, atomic force microscopy, molecular sieving, affinity chromatography technology, x-ray crystallography, two hybrid, biochemical, pull down, enzymatic study, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0016925 - protein sumoylation
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 267
Sc

1 1093
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024