HitPredict

Interactor 1: MED31 (P38633)
Mediator of RNA polymerase II transcription subunit 31 (Hpr1 suppressor protein 1) (Mediator complex subunit 31)
Gene: SOH1

Interactor 2: MED10 (Q06213)
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Negative regulator of URS2 protein 2)
Gene: NUT2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.717

The method score is based on:

Property Details
Experiments 11283351, 15477388, 27688401, 16554755, 37968396
Identification Methods two hybrid pooling approach, two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 127
Sc

1 157
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024