HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15324660
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 679 Hs			1 247
+	At
		788425 HS704_ARATH (48-664): 0: 885: 48.97		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	Hs
		503828 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		910222 HSP7C_MOUSE (51-653): 0: 883: 50.16		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	At
		612300 HS701_ARATH (48-673): 0: 878: 48.24		14333_ARATH (1-244): 4.4e-142: 400: 61.79
+	Hs
		503818 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	At
		612299 HS701_ARATH (48-673): 0: 878: 48.24		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	Hs
		503945 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	At
		250053 HSP7C_ARATH (48-673): 0: 865: 47.77		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	At
		612330 HS702_ARATH (48-673): 0: 862: 47.94		14332_ARATH (4-244): 1.39e-141: 398: 61.32
+	Hs
		503532 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		503857 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		713939 HS71L_HUMAN (49-673): 0: 883: 47.59		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		503478 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		751569 GRP75_HUMAN (1-679): 0: 873: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Mm
		565423 HSP72_MOUSE (50-669): 0: 864: 48.35		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Mm
		751909 GRP75_MOUSE (1-679): 0: 861: 98.38		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		503533 HSP7C_HUMAN (51-653): 0: 883: 50.16		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	At
		788477 HSP7F_ARATH (55-654): 0: 610: 54.23		14331_ARATH (4-244): 4.02e-141: 397: 59.67
+	Hs
		501743 BIP_HUMAN (53-677): 0: 566: 50.55		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Mm
		588711 BIP_MOUSE (53-677): 0: 567: 51.97		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59