HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 679 Hs			1 619
+	Hs
		503943 HSP7C_HUMAN (51-653): 0: 883: 50.16		REL_HUMAN (1-619): 0: 692: 100.00
+	Hs
		713949 HS71L_HUMAN (49-673): 0: 883: 47.59		REL_HUMAN (1-619): 0: 692: 100.00
+	Hs
		564060 HSP76_HUMAN (49-673): 0: 875: 48.68		REL_HUMAN (1-619): 0: 692: 100.00
+	Hs
		503938 HSP7C_HUMAN (51-653): 0: 883: 50.16		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		713948 HS71L_HUMAN (49-673): 0: 883: 47.59		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		564059 HSP76_HUMAN (49-673): 0: 875: 48.68		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		503415 HSP7C_HUMAN (51-653): 0: 883: 50.16		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		587444 HS71L_HUMAN (49-673): 0: 883: 47.59		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		564000 HSP76_HUMAN (49-673): 0: 875: 48.68		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		587456 GRP75_HUMAN (1-679): 0: 873: 100.00		NFKB1_HUMAN (1-375): 2e-145: 447: 37.47
+	Hs
		503913 HSP7C_HUMAN (51-653): 0: 883: 50.16		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		713946 HS71L_HUMAN (49-673): 0: 883: 47.59		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		564058 HSP76_HUMAN (49-673): 0: 875: 48.68		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		751582 GRP75_HUMAN (1-679): 0: 873: 100.00		RELB_HUMAN (2-479): 1.52e-143: 430: 35.04
+	Hs
		503906 HSP7C_HUMAN (51-653): 0: 883: 50.16		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Hs
		713945 HS71L_HUMAN (49-673): 0: 883: 47.59		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Hs
		564057 HSP76_HUMAN (49-673): 0: 875: 48.68		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Hs
		751580 GRP75_HUMAN (1-679): 0: 873: 100.00		NFKB2_HUMAN (2-385): 2.1e-133: 414: 34.88
+	Hs
		504030 HSP7C_HUMAN (51-653): 0: 883: 50.16		NFAC2_HUMAN (1-504): 1.26e-88: 296: 14.84
+	Hs
		317920 GRP75_HUMAN (1-679): 0: 873: 100.00		NFAC1_HUMAN (1-486): 1.55e-76: 264: 15.32