HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 679 Hs			1 1121
+	Hs
		504247 HSP7C_HUMAN (51-653): 0: 883: 50.16		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		502214 BIP_HUMAN (53-677): 0: 566: 50.55		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		504250 HSP7C_HUMAN (51-653): 0: 883: 50.16		NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13
+	Hs
		504388 HSP7C_HUMAN (51-653): 0: 883: 50.16		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		504792 HSP7C_HUMAN (51-653): 0: 883: 50.16		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		503764 HSP7C_HUMAN (51-653): 0: 883: 50.16		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		751721 GRP75_HUMAN (1-679): 0: 873: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		751841 GRP75_HUMAN (1-679): 0: 873: 100.00		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		125115 HSP7C_HUMAN (51-653): 0: 883: 50.16		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		871517 HSP72_HUMAN (50-653): 0: 868: 49.11		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		504760 HSP7C_HUMAN (51-653): 0: 883: 50.16		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		751829 GRP75_HUMAN (1-679): 0: 873: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		871786 HSP72_HUMAN (50-653): 0: 868: 49.11		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		504871 HSP7C_HUMAN (51-653): 0: 883: 50.16		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		504580 HSP7C_HUMAN (51-653): 0: 883: 50.16		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Sc
		478225 HSP77_YEAST (37-653): 0: 785: 66.61		RSP5_YEAST (29-320): 3.05e-17: 89.3: 13.99
+	Hs
		502315 BIP_HUMAN (53-677): 0: 566: 50.55		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		501878 BIP_HUMAN (53-677): 0: 566: 50.55		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		125114 BIP_HUMAN (53-677): 0: 566: 50.55		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		502449 BIP_HUMAN (53-677): 0: 566: 50.55		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47