HitPredict

Interactor 1: LAG1 (P38703)
Ceramide synthase LAG1 (Longevity assurance factor 1) (Longevity assurance gene 1 protein) (Longevity assurance protein 1) (Very-long-chain ceramide synthase LAG1) (EC 2.3.1.297)
Gene: LAG1

Interactor 2: LIP1 (Q03579)
Ceramide synthase subunit LIP1 (LAG1/LAC1-interacting protein 1)
Gene: LIP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	11283351, 15692566, 18719252, 37953642
Identification Methods	two hybrid pooling approach, affinity chromatography technology, two hybrid, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0046513 - ceramide biosynthetic process GO:0061576 - acyl-CoA ceramide synthase complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 411 Sc			1 150
+	Sc
		659188 LAC1_YEAST (20-389): 1.84e-133: 390: 74.05		LIP1_YEAST (1-150): 1.23e-118: 332: 100.00