HitPredict

Interactor 1: DBP8 (P38719)
ATP-dependent RNA helicase DBP8 (EC 3.6.4.13) (DEAD box protein 8)
Gene: DBP8

Interactor 2: ESF2 (P53743)
Pre-rRNA-processing protein ESF2 (18S rRNA factor 2)
Gene: ESF2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.707

The method score is based on:

Property Details
Experiments 29054886, 16772403, 37968396, 14690591
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005730 - nucleolus
and 2 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 431
Sc

1 316
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024