HitPredict

Interactor 1: DBP8 (P38719)
ATP-dependent RNA helicase DBP8 (EC 3.6.4.13) (DEAD box protein 8)
Gene: DBP8

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22199229, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 431 Sc			1 136
+	Hs
		828440 DDX49_HUMAN (1-423): 3.76e-164: 472: 47.20		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		934941 DDX42_HUMAN (2-427): 3.83e-123: 381: 31.64		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Sc
		624150 DBP2_YEAST (1-388): 2.77e-120: 362: 29.44		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		624221 DBP1_YEAST (1-416): 1.63e-113: 347: 30.02		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Sc
		415945 DED1_YEAST (1-400): 2.09e-123: 372: 28.78		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Sc
		624061 DBP2_YEAST (1-388): 2.77e-120: 362: 29.44		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		828333 DDX17_HUMAN (1-388): 3.77e-117: 360: 30.96		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		571355 DDX5_HUMAN (1-431): 3.93e-117: 356: 27.00		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		133927 DDX3X_HUMAN (1-391): 2.51e-114: 350: 30.41		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sc
		699712 DRS1_YEAST (3-379): 5.26e-61: 213: 36.34		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		757634 IF4A3_HUMAN (4-379): 1.09e-55: 191: 32.11		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03