HitPredict

Interactor 1: ECM29 (P38737)
Proteasome component ECM29 (Extracellular mutant protein 29)
Gene: ECM29

Interactor 2: PSA4 (P40303)
Proteasome subunit alpha type-4 (Macropain subunit PRE6) (Multicatalytic endopeptidase complex subunit PRE6) (Proteasome component PRE6) (Proteinase YSCE subunit PRE6)
Gene: PRE6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	18927584, 16429126, 37968396, 21321079
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1868 Sc			1 254
+	Sc
		619356 ECM29_YEAST (1-1868): 0: 1493: 100.00		PSA3_YEAST (4-207): 3.34e-40: 140: 35.29
+	Hs
		156310 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PSA7_HUMAN (4-234): 3.74e-95: 280: 58.01
+	Hs
		638148 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PSA4_HUMAN (3-233): 8.68e-91: 270: 31.49
+	Hs
		893689 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PSA6_HUMAN (2-239): 6.82e-91: 270: 29.75
+	Hs
		637449 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PSA1_HUMAN (2-249): 6.06e-90: 268: 31.35
+	Hs
		656251 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		637703 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PSA2_HUMAN (3-236): 1.56e-45: 154: 38.14
+	Sp
		1013778 ECM29_SCHPO (10-1650): 0: 776: 23.11		PSA4_SCHPO (1-252): 1.7e-93: 277: 55.95
+	Hs
		656268 CAND1_HUMAN (1380-1695): 2.42e-09: 64.7: 13.23		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		637714 CAND1_HUMAN (1380-1695): 2.42e-09: 64.7: 13.23		PSA2_HUMAN (3-236): 1.56e-45: 154: 38.14