HitPredict

Interactor 1: ECM29 (P38737)
Proteasome component ECM29 (Extracellular mutant protein 29)
Gene: ECM29

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	37968396, 16429126, 21321079
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1868 Sc			1 405
+	Sc
		753404 ECM29_YEAST (1-1868): 0: 1493: 100.00		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		703893 ECM29_YEAST (1-1868): 0: 1493: 100.00		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78
+	Hs
		907063 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95
+	Hs
		913292 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PRS10_HUMAN (20-402): 2.79e-124: 366: 43.34
+	Hs
		906856 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92
+	Hs
		798694 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04
+	Hs
		730285 ECM29_HUMAN (9-1753): 0: 1033: 22.20		PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05
+	Rn
		907220 CAND1_RAT (1380-1695): 2.5e-09: 64.7: 13.23		PRS8_RAT (3-405): 1.36e-129: 380: 73.95
+	Rn
		956841 CAND1_RAT (1380-1695): 2.5e-09: 64.7: 13.23		PRS7_RAT (60-390): 7.75e-109: 328: 50.75