HitPredict

Interactor 1: HSE1 (P38753)
Class E vacuolar protein-sorting machinery protein HSE1
Gene: HSE1

Interactor 2: VPS27 (P40343)
Vacuolar protein sorting-associated protein 27 (Golgi retention defective protein 11)
Gene: VPS27

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 12055639, 10688190, 20305637, 11805826, 11283351, 14581452, 15086794, 26601941, 16429126, 17543868, 31740006, 32029270, 34023781, 34599943, 20826334, 16554755, 18467557, 37968396, 22615397
Identification Methods coimmunoprecipitation, two hybrid, molecular sieving, tandem affinity purification, pull down, two hybrid pooling approach, affinity chromatography technology, x-ray crystallography, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~VHS, VHS~VHS
Common GO terms GO:0005768 - endosome
GO:0005774 - vacuolar membrane
GO:0006623 - protein targeting to vacuole
GO:0009306 - protein secretion
GO:0010008 - endosome membrane
and 12 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 452
Sc

1 622
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024