Interactor 1: LRP1 (P38801)
Exosome complex protein LRP1 (Like an rRNA processing protein 1) (Yeast C1D domain-containing protein) (rRNA processing protein 47)
Gene: LRP1

Interactor 2: RRP44 (Q08162)
Exosome complex exonuclease DIS3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Ribosomal RNA-processing protein 44)
Gene: DIS3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.55 0.716

The method score is based on:

Property Details
Experiments 12972615, 11805826, 12837249, 16554755, 14759368, 16429126, 28877463, 37968396
Identification Methods coimmunoprecipitation, tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0071028 - nuclear mRNA surveillance
and 2 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024