Interactor 1: LRP1 (P38801)
Exosome complex protein LRP1 (Like an rRNA processing protein 1) (Yeast C1D domain-containing protein) (rRNA processing protein 47)
Gene: LRP1
Interactor 2: RRP6 (Q12149)
Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.90 | 0.935 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12972615, 24106327, 12837249, 28877463, 25775092, 28539363, 29176610, 31662437, 19046973, 37968396, 38783922, 24937447, 23580640, 25319414, 16554755, 27076633, 17704127, 21135092, 14759368 |
| Identification Methods | coimmunoprecipitation, affinity chromatography technology, biochemical, x-ray crystallography, pull down, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HRDC~Sas10_Utp3, PMC2NT~Sas10_Utp3 |
| Common GO terms | GO:0000178 - exosome (RNase complex) GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery GO:0005634 - nucleus GO:0005730 - nucleolus and 6 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
