Interactor 1: ATG7 (P38862)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (Cytoplasm to vacuole targeting protein 2)
Gene: ATG7

Interactor 2: ATG3 (P40344)
Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3)
Gene: ATG3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 23142976, 22056771, 11139573, 11283351, 10688190, 17227760, 18719252, 38057553, 12965207, 22055191, 17986448, 22325599
Identification Methods cross-linking study, molecular sieving, coimmunoprecipitation, two hybrid pooling approach, two hybrid, light scattering, pull down, x-ray crystallography, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG7_N~Autophagy_act_C, Autophagy_act_C~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 630
Sc

1 310
+ Hs
+ Mm
+ At
+ Ce

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Last updated: 15 Jul 2024