HitPredict

Interactor 1: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Interactor 2: UBP6 (P43593)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	11029046, 11805826, 16554755, 16429126, 37968396
Identification Methods	coimmunoprecipitation, tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 268 Sc			1 499
+	Sp
		293410 RPN10_SCHPO (1-261): 5.8e-112: 323: 45.59		UBP6_SCHPO (5-499): 1.89e-113: 345: 37.02
+	Hs
		870711 PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15		UBP14_HUMAN (5-499): 1.27e-103: 320: 29.12
+	Mm
		192431 PSMD4_MOUSE (1-236): 7.75e-119: 346: 49.15		UBP8_MOUSE (17-498): 3.74e-81: 274: 15.10
+	Hs
		874192 PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15		UBP36_HUMAN (3-496): 3.71e-76: 261: 14.46
+	Hs
		874150 PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15		UBP7_HUMAN (100-347): 5.03e-30: 126: 21.26