HitPredict

Interactor 1: IF1A (P38912)
Eukaryotic translation initiation factor 1A (eIF-1A) (Eukaryotic translation initiation factor 4C) (eIF-4C)
Gene: TIF11

Interactor 2: IF2P (P39730)
Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)
Gene: FUN12

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.936

The method score is based on:

Property	Details
Experiments	12514125, 10982835, 17242201, 37968396, 21636924
Identification Methods	two hybrid, affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	direct interaction, physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	IF-2~eIF-1a
Common GO terms	GO:0001732 - formation of cytoplasmic translation initiation complex GO:0003743 - translation initiation factor activity GO:0005737 - cytoplasm GO:0006413 - translational initiation GO:0010494 - cytoplasmic stress granule and 2 others more... GO:0031369 - translation initiation factor binding GO:0033290 - eukaryotic 48S preinitiation complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	153
Sc

1	1002

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024