HitPredict

Interactor 1: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Interactor 2: NOM1 (Q5C9Z4)
Nucleolar MIF4G domain-containing protein 1 (SGD1 homolog)
Gene: NOM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 29395067, 35271311, 21576267
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~MA3, DEAD~MIF4G, Helicase_C~MA3, Helicase_C~MIF4G
Common GO terms GO:0003723 - RNA binding
GO:0005730 - nucleolus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 411
Hs

1 860
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024