HitPredict

Interactor 1: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 411 Hs			1 1121
+	Hs
		892830 IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		571491 DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		1153317 DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		125295 IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		892904 IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1154061 DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79		NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13
+	Hs
		181718 DDX3Y_HUMAN (17-410): 5.68e-143: 423: 32.45		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		571517 DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		571603 DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		125203 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		181736 DDX3Y_HUMAN (17-410): 5.68e-143: 423: 32.45		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Sc
		761942 DHH1_YEAST (39-408): 1.26e-169: 486: 40.54		RSP5_YEAST (29-320): 3.05e-17: 89.3: 13.99
+	Hs
		125142 DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		125617 DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		757761 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		571596 DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		181741 DDX3Y_HUMAN (17-410): 5.68e-143: 423: 32.45		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		757612 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		757781 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		757756 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05