HitPredict

Interactor 1: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	23084401, 20123736
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 411 Hs			1 955
+	Hs
		757780 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		640672 DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		757665 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		RBBP6_HUMAN (20-841): 1.66e-72: 264: 13.81
+	Hs
		892934 IF4A1_HUMAN (7-411): 1.67e-178: 505: 66.75		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		757803 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		571636 DDX5_HUMAN (25-411): 6.87e-135: 401: 30.63		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		134254 DDX3X_HUMAN (17-410): 2.28e-129: 388: 32.45		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		757612 IF4A3_HUMAN (1-411): 1.22e-142: 414: 100.00		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1154061 DDX17_HUMAN (14-411): 1.24e-132: 399: 30.79		NIPBL_HUMAN (138-674): 7.25e-11: 68.9: 13.20