Interactor 1: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1

Interactor 2: EXO1 (P39875)
Exodeoxyribonuclease 1 (EC 3.1.-.-) (Exodeoxyribonuclease I) (EXO I) (Exonuclease I) (Protein DHS1)
Gene: EXO1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.755

The method score is based on:

Property Details
Experiments 23435383, 12042306, 31351878, 33199619, 19015241, 12529393, 11901110, 11481425, 30061603, 17602897
Identification Methods isothermal titration calorimetry, two hybrid, affinity chromatography technology, unspecified method, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006298 - mismatch repair
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 769
Sc

1 702
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024