Interactor 1: MLH1 (P38920)
DNA mismatch repair protein MLH1 (MutL protein homolog 1) (Post meiotic segregation protein 2)
Gene: MLH1

Interactor 2: MLH2 (Q07980)
DNA mismatch repair protein MLH2 (MutL protein homolog 2)
Gene: MLH2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 10570173, 16554755, 16429126, 33303966, 28051769, 31351878, 36942481, 24811092
Identification Methods two hybrid, affinity chromatography technology, pull down, biochemical, coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3
Common GO terms GO:0000710 - meiotic mismatch repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006298 - mismatch repair
GO:0007131 - reciprocal meiotic recombination
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 769
Sc

1 695
+ Sc
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Dm
+ Ce
+ Dm
+ Ec
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024