Interactor 1: VPS45 (P38932)
Vacuolar protein sorting-associated protein 45
Gene: VPS45

Interactor 2: TLG2 (Q08144)
t-SNARE affecting a late Golgi compartment protein 2 (Syntaxin TLG2)
Gene: TLG2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 19667197, 11805826, 12756236, 10545112, 16769821, 18719252, 11879635, 37968396, 16429126
Identification Methods comigration in non denaturing gel electrophoresis, molecular sieving, tandem affinity purification, affinity chromatography technology, pull down, two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Sec1
Common GO terms GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 577
Sc

1 397
+ At
+ At
+ Mm
+ Hs
+ At
+ Rn
+ Rn
+ Sc
+ Hs
+ Mm
+ Hs
+ Mm
+ Rn
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024