Interactor 1: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A

Interactor 2: CD5R1 (Q15078)
Cyclin-dependent kinase 5 activator 1 (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin-dependent kinase 5 activator 1, p25 (p25) (Tau protein kinase II 23 kDa subunit) (p23)]
Gene: CDK5R1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15890360
Identification Methods surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 164
Hs

1 307
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024