HitPredict

Interactor 1: HAL5 (P38970)
Serine/threonine-protein kinase HAL5 (EC 2.7.11.1) (Halotolerance protein 5)
Gene: HAL5

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	16319894
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 855 Sc			1 700
+	Hs
		256264 PKN1_HUMAN (5-853): 6.4e-132: 419: 14.27		BRE1B_HUMAN (315-700): 1.27e-34: 143: 20.73
+	At
		1247415 CIPK5_ARATH (494-853): 1.67e-119: 371: 18.89		BRE1A_ARATH (136-700): 2.44e-43: 170: 16.53
+	Hs
		522542 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH1_HUMAN (2-643): 3.75e-26: 117: 10.19
+	Dm
		397193 KPC1_DROME (177-855): 1.98e-118: 376: 13.33		MYSN_DROME (228-666): 6.66e-13: 74.7: 9.46
+	Hs
		522604 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH7_HUMAN (4-511): 1.08e-17: 90.1: 10.29
+	Hs
		625176 CDK2_HUMAN (500-849): 3.74e-114: 351: 18.90		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		625177 CDK2_HUMAN (500-849): 3.74e-114: 351: 18.90		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88
+	Hs
		625530 CDK2_HUMAN (500-849): 3.74e-114: 351: 18.90		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		528401 CDK2_HUMAN (500-849): 3.74e-114: 351: 18.90		MYH8_HUMAN (2-432): 2.35e-13: 76.2: 9.98
+	Hs
		960128 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH2_HUMAN (319-661): 1.17e-13: 77: 11.59
+	Hs
		528405 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH8_HUMAN (2-432): 2.35e-13: 76.2: 9.98
+	Hs
		502908 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH3_HUMAN (2-437): 1.4e-12: 73.5: 10.31
+	Hs
		528368 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH6_HUMAN (291-661): 1.01e-11: 70.9: 10.53
+	Hs
		960130 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH15_HUMAN (1-425): 1.71e-11: 70.1: 10.54
+	Hs
		551610 CDK2_HUMAN (500-849): 3.74e-114: 351: 18.90		DESP_HUMAN (127-645): 9.85e-10: 64.2: 14.61
+	Hs
		960129 CDK3_HUMAN (500-849): 6.81e-113: 348: 19.18		MYH13_HUMAN (282-661): 2.33e-09: 63.1: 11.58
+	Rn
		871291 AAPK1_RAT (485-840): 7.72e-87: 289: 23.03		MYH9_RAT (255-666): 4.36e-18: 91.3: 12.47
+	Rn
		871335 AAPK1_RAT (485-840): 7.72e-87: 289: 23.03		MYH10_RAT (245-667): 1.83e-16: 86.3: 10.64
+	Rn
		102485 AAPK1_RAT (485-840): 7.72e-87: 289: 23.03		G3V6P7_RAT (366-657): 6.94e-09: 61.6: 12.00