HitPredict

Interactor 1: TEM1 (P38987)
Protein TEM1
Gene: TEM1

Interactor 2: IQG1 (Q12280)
Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1)
Gene: IQG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.80	0.700

Property	Details
Experiments	9950677, 23966170
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Sc			1 1495
+	Hs
		1040022 RAB35_HUMAN (13-213): 1.9e-77: 234: 23.53		IQGA2_HUMAN (88-1492): 0: 853: 15.36
+	Hs
		1070446 RAB35_HUMAN (13-213): 1.9e-77: 234: 23.53		NGAP_HUMAN (827-1380): 1.53e-88: 316: 9.50
+	Hs
		914440 RB11A_HUMAN (10-208): 4.8e-77: 233: 19.50		NGAP_HUMAN (827-1380): 1.53e-88: 316: 9.50
+	Zm
		14343 B4FNJ6_MAIZE (16-219): 7.93e-79: 237: 19.51		A0A1D6G388_MAIZE (416-1342): 3.74e-76: 282: 9.57
+	Hs
		1070242 RAB35_HUMAN (13-213): 1.9e-77: 234: 23.53		DAB2P_HUMAN (815-1259): 9.6e-74: 271: 9.78
+	Hs
		918932 RAB1A_HUMAN (10-217): 6.68e-82: 245: 21.05		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Mm
		99942 RAB1A_MOUSE (10-217): 6.68e-82: 245: 21.05		SYGP1_MOUSE (815-1224): 2.13e-66: 249: 13.10
+	At
		1338479 RABD1_ARATH (13-220): 4.54e-77: 233: 23.33		MYO6_ARATH (294-1030): 1.2e-69: 260: 11.08
+	Hs
		1061919 RAB35_HUMAN (13-213): 1.9e-77: 234: 23.53		GAPD1_HUMAN (751-1282): 6.49e-68: 255: 11.73
+	Hs
		1070348 RAB35_HUMAN (13-213): 1.9e-77: 234: 23.53		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Rn
		914521 RB11A_RAT (10-208): 4.8e-77: 233: 19.50		MYO5B_RAT (184-1030): 9.01e-68: 255: 10.03
+	Hs
		914291 RB11A_HUMAN (10-208): 4.8e-77: 233: 19.50		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Hs
		914084 RB11A_HUMAN (10-208): 4.8e-77: 233: 19.50		CNN3_HUMAN (90-366): 7.13e-64: 222: 15.04
+	Hs
		809313 RAB35_HUMAN (13-213): 1.9e-77: 234: 23.53		IQGA1_HUMAN (88-1320): 2.1e-49: 195: 12.22
+	Hs
		914303 RB11A_HUMAN (10-208): 4.8e-77: 233: 19.50		CNN2_HUMAN (78-366): 1.65e-50: 183: 12.80
+	Hs
		845335 RAB7A_HUMAN (16-207): 1.17e-15: 74.7: 26.40		NGAP_HUMAN (827-1380): 1.53e-88: 316: 9.50
+	Hs
		845181 RAB7A_HUMAN (16-207): 1.17e-15: 74.7: 26.40		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Hs
		894725 RAB8A_HUMAN (13-216): 9.43e-78: 234: 20.00		TAGL_HUMAN (98-243): 5.11e-16: 80.3: 25.64
+	Hs
		741853 RB11A_HUMAN (10-208): 4.8e-77: 233: 19.50		TAGL2_HUMAN (106-243): 3.48e-13: 71.8: 17.57