Interactor 1: SMC2 (P38989)
Structural maintenance of chromosomes protein 2 (DA-box protein SMC2)
Gene: SMC2

Interactor 2: SMC4 (Q12267)
Structural maintenance of chromosomes protein 4
Gene: SMC4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 10811823, 12719426, 26904946, 16554755, 37968396, 21441928
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, biochemical, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SMC_hinge~SMC_hinge, SMC_N~SMC_N
Common GO terms GO:0000070 - mitotic sister chromatid segregation
GO:0000796 - condensin complex
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1170
Sc

1 1418
+ Hs
+ Sp
+ Xl
+ Ce
+ Ce
+ Sc
+ Sc
+ Hs
+ Bt
+ Hs
+ Mm
+ Hs
+ Xl
+ Xl
+ Mm
+ Xl

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Last updated: 15 Jul 2024