Interactor 1: STT3 (P39007)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Oligosaccharyl transferase subunit STT3) (EC 2.4.99.18) (Staurosporine and temperature sensitivity protein 3)
Gene: STT3

Interactor 2: OST1 (P41543)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (N-linked oligosaccharyl transferase subunit 1) (Oligosaccharyl transferase 64 kDa subunit) (Oligosaccharyl transferase subunit OST1) (Oligosaccharyl transferase subunit alpha)
Gene: OST1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 9435788, 9405463, 11805826, 12805367, 16096346, 32938717, 37968396, 16429126, 14530272
Identification Methods affinity chromatography technology, coimmunoprecipitation, tandem affinity purification, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribophorin_I~STT3
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0008250 - oligosaccharyltransferase complex
GO:0018279 - protein N-linked glycosylation via asparagine
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 718
Sc

1 476
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024