HitPredict

Interactor 1: STT3 (P39007)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Oligosaccharyl transferase subunit STT3) (EC 2.4.99.18) (Staurosporine and temperature sensitivity protein 3)
Gene: STT3

Interactor 2: OST3 (P48439)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 (Oligosaccharyl transferase 34 kDa subunit) (Oligosaccharyl transferase subunit OST3) (Oligosaccharyl transferase subunit gamma)
Gene: OST3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.954

The method score is based on:

Property Details
Experiments 9405463, 12805367, 16096345, 16297388, 12810948, 32938717, 37968396
Identification Methods coimmunoprecipitation, affinity chromatography technology, protein complementation assay, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains OST3_OST6~STT3
Common GO terms GO:0004579 - dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006487 - protein N-linked glycosylation
GO:0008250 - oligosaccharyltransferase complex
and 1 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 718
Sc

1 350
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024