HitPredict

Interactor 1: END3 (P39013)
Actin cytoskeleton-regulatory complex protein END3 (Endocytosis protein 3)
Gene: END3

Interactor 2: AP18B (P53309)
Clathrin coat assembly protein AP180B
Gene: YAP1802

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	11940605, 19591838, 22875988
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 349 Sc			1 568
+	Sc
		710396 EDE1_YEAST (3-262): 2.31e-26: 112: 16.73		AP18B_YEAST (1-568): 8.21e-139: 416: 100.00
+	Hs
		787907 EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69		PICAL_HUMAN (3-557): 9.13e-119: 367: 18.66
+	Sc
		704779 END3_YEAST (1-349): 6.37e-81: 252: 100.00		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Sc
		692238 PAN1_YEAST (4-82): 2.84e-14: 76.1: 27.50		AP18B_YEAST (1-568): 8.21e-139: 416: 100.00
+	Rn
		222940 EHD2_RAT (77-223): 1.21e-13: 73.8: 17.69		PICAL_RAT (3-557): 8.9e-120: 369: 19.81
+	Hs
		237877 EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69		AP180_HUMAN (3-488): 4.01e-89: 296: 20.40
+	Hs
		1036409 ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30		PICAL_HUMAN (3-557): 9.13e-119: 367: 18.66
+	Ce
		1353623 Q9U2T9_CAEEL (3-349): 2.24e-16: 82.3: 11.75		PICAL_CAEEL (3-522): 3.15e-111: 345: 23.11
+	Sc
		692225 PAN1_YEAST (4-82): 2.84e-14: 76.1: 27.50		AP18A_YEAST (3-558): 4.03e-111: 346: 44.33
+	Sc
		704769 EDE1_YEAST (3-262): 2.31e-26: 112: 16.73		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Hs
		124413 ITSN1_HUMAN (124-241): 2.14e-09: 61.1: 12.30		HIP1_HUMAN (4-364): 6.6e-89: 297: 13.79
+	Sc
		692213 PAN1_YEAST (4-82): 2.84e-14: 76.1: 27.50		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Hs
		253734 EPS15_HUMAN (10-348): 7.95e-34: 134: 15.69		AUXI_HUMAN (265-562): 5.33e-27: 118: 11.80