HitPredict

Interactor 1: MET30 (P39014)
F-box protein MET30 (E3 ubiquitin ligase complex SCF(Met30) subunit MET30) (Methionine-requiring protein 30)
Gene: MET30

Interactor 2: SKP1 (P52286)
Suppressor of kinetochore protein 1 (Centromere DNA-binding protein complex CBF3 subunit D) (E3 ubiquitin ligase complex SCF subunit SKP1)
Gene: SKP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 10688190, 14660673, 9716410, 11805837, 11283612, 12582129, 15660125, 18719252, 21172660, 20581845, 23000173, 22817900, 10637232, 10582239, 32817489, 37968396, 38719837, 24648496, 19882662, 14690591 and 1 others

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Identification Methods two hybrid, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, pull down, protein complementation assay, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0007346 - regulation of mitotic cell cycle
and 3 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 640
Sc

1 194
+ Mm
+ Hs
+ Hs
+ Ce
+ Dm
+ Sc
+ Mm
+ Sp
+ Hs
+ Sp
+ Hs
+ Xl
+ Mm
+ Hs
+ Sp
+ Dm
+ Dm
+ Sp
+ Dm
+ Dm

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Last updated: 15 Jul 2024