HitPredict

Interactor 1: DYN1 (P39053)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: Dnm1

Interactor 2: PROF2 (Q9JJV2)
Profilin-2 (Profilin II)
Gene: Pfn2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	9463375, 16319076
Identification Methods	affinity chromatography technology, peptide array, anti bait coimmunoprecipitation, pull down, cosedimentation in solution
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding GO:0005737 - cytoplasm GO:0050804 - modulation of chemical synaptic transmission GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 867 Mm			1 140
+	Mm
		760438 DYN1_MOUSE (1-867): 0: 1087: 100.00		PROF1_MOUSE (1-140): 2.28e-75: 222: 62.86
+	Hs
		128405 DNM1L_HUMAN (6-750): 0: 773: 38.82		PROF1_HUMAN (1-140): 6.4e-76: 223: 61.43