HitPredict

Interactor 1: DYN1 (P39055)
Dynamin (EC 3.6.5.5)
Gene: dyn-1

Interactor 2: VAV (Q45FX5)
Protein vav-1
Gene: vav-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Dynamin_M~PH, GED~PH, C1_1~PH, PH~PH, PH~RhoGEF
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 830 Ce			1 1007
+	Hs
		840758 DYN2_HUMAN (5-830): 0: 982: 63.05		TIAM2_HUMAN (132-831): 1.99e-73: 268: 13.89
+	Mm
		1141147 DYN3_MOUSE (5-830): 0: 1001: 63.76		GRB2_MOUSE (801-990): 1.62e-74: 246: 30.73
+	Mm
		760450 DYN1_MOUSE (5-826): 0: 995: 62.05		GRB2_MOUSE (801-990): 1.62e-74: 246: 30.73
+	Hs
		924499 DYN1_HUMAN (5-820): 0: 996: 62.07		GRB2_HUMAN (801-990): 3.81e-74: 245: 30.73
+	Rn
		599402 DYN1_RAT (5-820): 0: 991: 62.31		GRB2_RAT (801-990): 3.81e-74: 245: 30.73
+	Mm
		760474 DYN2_MOUSE (5-830): 0: 986: 63.59		GRB2_MOUSE (801-990): 1.62e-74: 246: 30.73
+	Hs
		924956 DYN3_HUMAN (5-830): 0: 987: 62.43		GRB2_HUMAN (801-990): 3.81e-74: 245: 30.73
+	Hs
		840663 DYN2_HUMAN (5-830): 0: 982: 63.05		GRB2_HUMAN (801-990): 3.81e-74: 245: 30.73
+	Mm
		760469 DYN1_MOUSE (5-826): 0: 995: 62.05		ITSN1_MOUSE (404-1007): 2.14e-27: 122: 10.83
+	Mm
		760488 DYN2_MOUSE (5-830): 0: 986: 63.59		ITSN1_MOUSE (404-1007): 2.14e-27: 122: 10.83
+	Ce
		666206 DYN1_CAEEL (1-762): 0: 986: 100.00		SEM5_CAEEL (826-1002): 2.15e-19: 90.1: 33.89
+	Hs
		840686 DYN2_HUMAN (5-830): 0: 982: 63.05		GRAP_HUMAN (831-988): 4.34e-17: 83.2: 34.36
+	Rn
		599413 DYN1_RAT (5-820): 0: 991: 62.31		ITSN1_RAT (132-997): 4.93e-12: 72.6: 10.39
+	Hs
		983379 DYN1_HUMAN (5-820): 0: 996: 62.07		ITSN1_HUMAN (403-1006): 1.16e-09: 64.9: 10.48
+	Hs
		840702 DYN2_HUMAN (5-830): 0: 982: 63.05		ITSN1_HUMAN (403-1006): 1.16e-09: 64.9: 10.48
+	Dm
		649302 DYN_DROME (8-830): 0: 949: 65.58		GRAP_DROME (825-989): 5.8e-17: 82.4: 29.76