Interactor 1: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 12435733
Identification Methods two hybrid, solid phase assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005604 - basement membrane
GO:0005615 - extracellular space
GO:0008285 - negative regulation of cell population proliferation
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1754
Hs

1 4391
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Mm
+ Dm

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Last updated: 15 Jul 2024