HitPredict

Interactor 1: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Interactor 2: SFPA2 (Q8IWL1)
Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5)
Gene: SFTPA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005581 - collagen trimer GO:0005615 - extracellular space
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1754 Hs			1 248
+	Hs
		473745 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59
+	Hs
		70507 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1T9B_HUMAN (28-106): 3.17e-12: 67: 46.59
+	Hs
		760531 COIA1_HUMAN (1-1754): 0: 1036: 99.60		ADIPO_HUMAN (23-92): 3.96e-11: 63.2: 51.95
+	Hs
		358657 COIA1_HUMAN (1-1754): 0: 1036: 99.60		CO4A1_HUMAN (28-101): 1.65e-09: 59.7: 55.26
+	Hs
		358644 CO4A1_HUMAN (783-1673): 7.78e-70: 262: 22.25		CO4A1_HUMAN (28-101): 1.65e-09: 59.7: 55.26
+	Hs
		358660 CO4A1_HUMAN (783-1673): 7.78e-70: 262: 22.25		CO7A1_HUMAN (28-105): 3.26e-09: 58.9: 48.72
+	Hs
		441048 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59
+	Hs
		358648 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		CO4A1_HUMAN (28-101): 1.65e-09: 59.7: 55.26
+	Hs
		441055 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		CO9A1_HUMAN (28-103): 4.15e-09: 58.5: 51.32
+	Hs
		441078 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		COLA1_HUMAN (28-105): 4.63e-09: 58.2: 42.17
+	Hs
		358590 CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83		C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59
+	Hs
		70495 CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83		C1T9B_HUMAN (28-106): 3.17e-12: 67: 46.59
+	Mm
		1144386 CO7A1_MOUSE (1240-1670): 7.73e-28: 125: 16.89		CO7A1_MOUSE (28-101): 5.32e-09: 58.2: 41.94
+	Hs
		358596 CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83		CO9A1_HUMAN (28-103): 4.15e-09: 58.5: 51.32
+	Mm
		358670 CO4A1_MOUSE (1165-1682): 1.27e-24: 115: 19.65		CO4A1_MOUSE (28-101): 2.93e-09: 58.9: 55.26
+	Mm
		93247 E9PWQ3_MOUSE (1558-1684): 6.7e-12: 73.1: 10.53		E9PWQ3_MOUSE (19-152): 1.68e-14: 74.7: 18.49
+	Hs
		358498 CO1A1_HUMAN (614-901): 6.51e-11: 70.1: 24.83		CO7A1_HUMAN (28-105): 3.26e-09: 58.9: 48.72