Interactor 1: SSN3 (P39073)
Meiotic mRNA stability protein kinase SSN3 (EC 2.7.11.22) (EC 2.7.11.23) (Cyclin-dependent kinase 8) (Suppressor of RNA polymerase B SRB10)
Gene: SSN3
Interactor 2: SSN8 (P47821)
RNA polymerase II holoenzyme cyclin-like subunit (Suppressor of RNA polymerase B 11)
Gene: SSN8
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7732022, 7877695, 12200444, 9488431, 17689156, 33523904, 37968396, 11226276, 9702190, 24043446, 29438513, 33933450, 11525400, 23563140, 24554767 |
| Identification Methods | coimmunoprecipitation, affinity chromatography technology, two hybrid, pull down, biochemical, enzymatic study, protein complementation assay, x-ray crystallography, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cyclin_N~Pkinase |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0016592 - mediator complex GO:1990508 - CKM complex |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
