HitPredict

Interactor 1: TCPB (P39076)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)
Gene: CCT2

Interactor 2: HOS2 (P53096)
Probable histone deacetylase HOS2 (EC 3.5.1.98)
Gene: HOS2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 527 Sc			1 452
+	Hs
		1038670 TCPH_HUMAN (2-517): 0: 570: 34.36		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		826651 TCPG_HUMAN (2-525): 0: 552: 27.15		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		826803 TCPG_HUMAN (2-525): 0: 552: 27.15		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Hs
		943219 TCPB_HUMAN (2-526): 0: 544: 65.59		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		177367 TCPH_HUMAN (2-517): 0: 570: 34.36		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Sc
		792389 TCPH_YEAST (3-527): 0: 537: 32.26		HOS2_YEAST (1-452): 0: 573: 100.00
+	Hs
		573251 TCPA_HUMAN (10-526): 0: 527: 33.02		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		573401 TCPA_HUMAN (10-526): 0: 527: 33.02		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Sc
		760777 TCPG_YEAST (2-522): 0: 527: 27.05		HOS2_YEAST (1-452): 0: 573: 100.00
+	Sc
		693016 TCPB_YEAST (1-527): 0: 553: 100.00		RPD3_YEAST (10-439): 0: 546: 44.60
+	Hs
		177233 TCPG_HUMAN (2-525): 0: 552: 27.15		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Hs
		177257 TCPB_HUMAN (2-526): 0: 544: 65.59		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Sc
		693035 TCPH_YEAST (3-527): 0: 537: 32.26		RPD3_YEAST (10-439): 0: 546: 44.60
+	Sp
		140638 TCPH_SCHPO (1-524): 0: 559: 32.83		PHD1_SCHPO (24-425): 0: 518: 57.96
+	Sc
		693017 TCPG_YEAST (2-522): 0: 527: 27.05		RPD3_YEAST (10-439): 0: 546: 44.60
+	Hs
		177188 TCPA_HUMAN (10-526): 0: 527: 33.02		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Hs
		177231 TCPE_HUMAN (2-514): 0: 526: 33.65		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Sp
		140519 TCPG_SCHPO (2-523): 0: 537: 26.37		PHD1_SCHPO (24-425): 0: 518: 57.96
+	Mm
		945920 TCPH_MOUSE (2-526): 0: 575: 33.96		HDAC4_MOUSE (2-423): 9.4e-145: 442: 23.09
+	Mm
		945965 TCPE_MOUSE (2-514): 0: 564: 33.65		HDAC4_MOUSE (2-423): 9.4e-145: 442: 23.09